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[PMC free article] [PubMed] [Google Scholar] 21.Esteve-Rudd J., Fernández-Sánchez L., Lax P., De Juan E., Martín-Nieto J., Cuenca N

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In addition to their direct effects on sleep, glucocorticoids might also modulate sleep indirectly by influencing the activity of the circadian clock system (from the Latin “circa diem” meaning “approximately a day”), a highly conserved timekeeping system that creates internal rhythmicity under the influence of day/night cycles (55-57)