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8.5 Cell-free strategies In recent years, researchers have discovered that extracellular vesicles (EVs) secreted by stem cells, such as exosomes and microvesicles, possess immunomodulatory functions similar to stem cells (Mendt et al., 2019

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Conversely, excessive glucose intake has been observed to reduce microbial diversity in animal models, contributing to the advancement of age-related diseases [141]