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In contrast, E h of the Cys/CySS couple was −145 ± 3 mV under proliferative conditions and oxidized by about 30 mV by either the differentiation agent, sodium butyrate, or the GSH synthesis inducer benzyl isothiocyanate (92)

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Research on glutathione-related enzymes, such as glutathione synthase (GSS), glutathione reductase (GR), and glutathione peroxidase (GPx), reveals their key roles in glutathione synthesis, regeneration, and functional maintenance (Frustaci et al., 2012