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Steviol, the primary metabolite, may accumulate in the kidneys via entero-renal circulation, imposing further stress on the glomeruli and proximal tubules, consistent with previous findings of stevia-induced nephrotoxicity (Toskulkao et al., 1994)

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For example, ketogenic diets (KDs) are dietary patterns defined by high fat intake, moderate to low protein consumption, and extremely low carbohydrate intake (50 g), and they may target cancer cell (CC) metabolism in cancer settings, potentially altering tumor treatment and prognosis