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In a study conducted in the Netherlands, most of the patients complained about neurotoxicity in the upper and lower extremities 6 months after cessation of chemotherapy with oxaliplatin, paclitaxel, or docetaxel (78.8 and 89.7%, respectively) (Beijers A

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70 Additionally, physiological levels of ROS, particularly H 2 O 2, can modulate numerous prosurvival pathways and transcription factors involved in cell cycle progression

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