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2021;44 doi: 10.1016/j.tmaid.2021.102168

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Human DCs express TrkB, and exogenous BDNF or NT-4 directly modulates their maturation, consistent with a capacity for TrkB ligands to alter costimulation and cytokine output during antigen presentation ( Endothelial and perivascular programs offer a second axis through which neurotrophins can reshape antitumor immunity