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These require significantly more documentation to avoid automatic denial: J3490 — Unclassified drugs (non-chemotherapy) J3590 — Unclassified biologics J9999 — Not otherwise classified, antineoplastic drugs When submitting an unclassified code, include the drug name, dosage, NDC number, and wholesale acquisition cost (WAC) or invoice price in the claim notes or attachment

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documented vial-specific handling references such as the 5-Amino-1MQ 50 mg vial protocol and the corresponding 10 mg vial protocol exist to keep laboratory concentration arithmetic explicit and reproducible rather than improvised