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Vaseline Glutaglow Bright & Smooth Ampoule Serum Deodorant 45Ml - Smoothing Brightening Deodorant For Soft Even Underarms
[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Edwards D.G., Gauthier A.L., Hayman M.A., Lang J.T., Kenefick R.W
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Duration:10 Minutes
The mechanisms of action of HSE include (1) anti-androgen by non-selective inhibition of both type I and type II isoenzymes of 5α-reductase versus finasteride, which selectively inhibits only the type II 5α-reductase enzyme [149], (2) pro-apoptotic by inhibition of the growth of the prostate via blockade of insulin-like growth factor-1, plus the increased B-cell lymphoma-associated X (Bax)/Bcl2 ratio observed in prostate tissue sample from subjects (via oral dosing of HSE at 320 mg daily for 3 months compared to untreated control values) [149,156], and (3) anti-inflammatory actions by significantly reduced expression of inflammation-regulated genes including IL-6, CCL-5, CCL-2, COX-2, and iNos plus the downregulation of other pro-inflammatory factors [149,150,151,152]
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