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Interestingly, PMA stimulation showed a distinct response, showing a decline in phosphocholine between 10 and 15 minutes, indicating a stimulus-dependent, distinct regulatory mechanism of phosphocholine metabolism (92)

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Furthermore, it is important to note that viral infections, such as that caused by EBV, can trigger both CD8 T-cell autoimmune responses and the production of autoantibodies against the adenohypophysis, due to the expression of viral antigens that exhibit molecular similarity to ACTH (243, 304)