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MADD is caused by deficiency of one of the two electron-transfer flavoproteins which transfer electrons from acyl-CoA dehydrogenases to Coenzyme Q in the respiratory chain: Electron Transfer Flavoprotein (ETF), encoded by ETFA and ETFB genes, and electron-transfer flavoprotein dehydrogenase (ETFDH), encoded by ETFDH [136]

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The British National Formulary (BNF), the British Society of Haematology Guidelines, NHS Clinical Knowledge guides, Integrated Care Board guidance notes such as this one from NHS Cambridgeshire and Peterborough, Vitamin B12 full guidance