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The silymarin standard group displayed no histopathological alterations in most liver sections, with only a few binucleations of hepatocytes observed in some areas (Figures 11E, F), and apparent normal renal parenchyma, although some renal tubules exhibited mild vacuolar degeneration (Figures 12E, F)
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Because SCFAs and other anaerobe-associated metabolites contribute to epithelial redox homeostasis, oxygen-driven community shifts may lower antioxidant buffering and thereby increase ferroptotic vulnerability during inflammation (118)
