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Researchers modified this fragment by adding a tyrosine residue to improve its stability, producing a compound structurally distinct from both full-length growth hormone and GHRH analogs like tesamorelin

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In women undergoing ovulation induction, an excessive ovarian response to follicular stimulating agents may lead to the development of ovarian hyperstimulation syndrome if Human Chorionic Gonadotropin is given to induce ovulation or to support the corpus luteum