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Development of insulin resistance and subsequent glucotoxic conditions can progress to chronic disorders, such as non-alcoholic fatty liver disease (NAFLD), characterized by excessive lipid accumulation, and non-alcoholic steatohepatitis (NASH), characterized by increased extracellular matrix (ECM) deposition [80,81]

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Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia