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Metformin is associated with low levels of vitamin B12 with no effect on other vitamin levels. A selective action of metformin - Nutrition, Metabolism and Cardiovascular Diseases

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While most people can benefit from a B12 injection, certain groups of people may see more obvious benefits than others: People With Signs Of B12 Deficiency Any person with the signs or symptoms of a B12 deficiency should pay a visit to their doctor, but an injection may still provide them with benefits