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At rest, l-CIT has reduced BP, wave reflection and PWV in middle-aged adults with increased BP and/or arterial stiffness ( Reference Ochiai, Hayashi and Morita 17 , Reference Figueroa, Wong and Hooshmand 18 ) , but not in young, healthy men ( Reference Figueroa, Trivino and Sanchez-Gonzalez 4 )

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PQN-75 is expressed in the pharyngeal gland cells of Caenorhabditis elegans and is dispensable for germline development