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Figure 1 4.1.1 VC promotes muscle development The complex process of skeletal muscle development is regulated by myogenic regulatory factors (MRFs), including myoblast determination protein 1 (MyoD), myogenic factor 5 (Myf5), and myogenin (MyoG) ( Piaractus mesopotamicus ) myoblasts, VC supplementation enhances MyoG expression and promotes cell proliferation and migration, partly by strengthening antioxidant defenses against menadione-induced oxidative injury ( As an essential cofactor for DNA and histone demethylases, VC also contributes to the epigenetic regulation of myogenesis ( 4.1.2 VC regulates muscle regeneration by modulating MuSC fate MuSCs, also known as satellite cells, are essential for skeletal muscle growth, repair, and regeneration
