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Finally, in vitro studies have shown the potential of NAC (1nM) to disassemble fibrils, protofibrils, oligomers and dimers of Aβ molecules by blocking continuity in their oligomerization, a phenomenon mediated by the formation of hydrogen bridges between the Aβ molecule and NAC, and by the stabilization of the neprilysin protease which is part of the catabolic equilibrium of the Aβ peptide [70,71,72]
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To determine if intestinal dysbacteriosis was induced by florfenicol, 11 koi carp from each of these two groups were sacrificed seven days after florfenicol intake, and a fecal sample from each fish was collected