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The pharmacological profile of GHK-Cu observed in preclinical models covers a broad spectrum of activity: Stimulation of extracellular matrix synthesis — influence on the production of collagen, elastin and glycosaminoglycans in dermal fibroblasts Pro-regenerative and pro-angiogenic effects — in in vivo and in vitro wound healing models Modulation of gene expression — in transcriptomic studies, the impact on hundreds of tissue repair and antioxidant defense genes Transport of copper ions — GHK as a physiological carrier of Cu²⁺, a cofactor of matrix enzymes Antioxidant and anti-inflammatory activity — reduction of oxidative stress markers in cell models GHK-Cu is a model ligand for testing in the group of plasma peptides connective tissue remodeling and copper biology — combines a signaling function with trace element transport, making it a tool for studying the interface between copper metabolism and extracellular matrix repair

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